Baycox (toltrazuril) is the result of Bayer research efforts. Thanks to its characteristics, it represents a new standard in coccidiosis control in Race Horses, Camels, Pigeons, Greyhounds & Alpacas.

Baycox belongs to the chemical group of “symmetric triazinons” and is not chemically related to any other anticoccidial drug currently used in veterinary medicine. This is a 5% solution.

Due to its particular mode of action, which affects all intracellular structures of Coccidia, Baycox demonstrates very high efficacy, as shown by the following benefits:

Coccidiosis:

Coccidiosis is an infection of intestinal epithelium caused by protozoan parasite of family Eimeriidae.

All livestock species, as well as wild animals, can be infected. Coccidiosis is especially prevalent when birds or mammals are grouped together. Coccidia oocysts are highly resistant to environment conditions, and disinfectants, making coccidiosis control difficult.

Coccidiosis is characterised by an invasion of the intestinal wall by the Coccidia parasite. The parasite then goes through several stages of growth and multiplication, during which damage occurs to the mucosal and submucosal tissues of the intestine.

Depending on the Coccidia strain involved and the animal species affected, the disease complexes can range from subclinical infections to infections that include severe intestinal problems with severe lesions in the gastrointestinal tract, to diarrhoea that can result in high mortality and/or a negative impact on the factors of production.

For the aforementioned reasons, several research institutes have put a great deal of effort into developing different options for controlling coccidiosis. Bayer, for example, developed Baycox (toltrazuril), which represents one of the most efficient ways to control and prevent coccidiosis in various animal species.

Baycox demonstrates powerful anticoccidial activity against different stages in the life cycles of the various Eimeria spp. of birds and mammals. It has produced excellent results in therapeutic and metaphylactic programs for a range of animal species.

Toltrazuril - Mode of Action -Toltrazuril (Baycox) damages all intracellular development stages of Eimeria (= Coccidia). Toltrazuril affects schizonts, micro- and macrogametes, but not the tissue cells of the host animals, as was shown in light and electron microscopic studies.

These findings suggest that toltrazuril interferes with the division of the nucleus and with the activity of the mitochondria, which is responsible for the respiratory metabolism of Coccidia.

In the magrometes, toltrazuril damages the so-called wall-forming bodies. In all intracellular developmental stages, severe vacuolisation occurs due to inflation of the endoplasmatic reticulum.

Toltrazuril thus has a coccidiocidal mode of action.

The special mode of action results in the following advantages:

* toltrazuril acts on all intracellular developmental stages,

* toltrazuril does not interfere with the development of immunity

*follow-up treatment usually is not necessary

*even an advanced infection (after 3 – 5 days; gametogony) can still be treated successfully,

*the efficacy of toltrazuril is independent of the severity of the infection.