LIMITED AVAILABILITY
Blood Building Peptide is for rapidly increasing RBC & Hemoglobin in Race Horses & Camels.
Blood Building Peptide is an erythropoiesis-stimulating agent (ESA) that is being tested in clinical
trials for the treatment of anemia associated with chronic renal
failure (CRF). Trials are
evaluating the ability of this peptide to correct anemia by raising and
maintaining hemoglobin (Hgb) levels within a target of 10-12 or 11-12
g/dL, depending on the situation.
In contrast to the current standard of care, recombinant
protein-based ESAs, Blood Building Peptide is a novel, synthetic peptide-based ESA
that is immunologically distinct from endogenous human erythropoietin
(EPO), a protein produced by the kidneys to stimulate the production of
oxygen-transporting red blood cells. The most advanced portion of
Blood Building Peptide clinical development program is an ongoing Phase 3 program
that consists of four studies (two in dialysis, two in non-dialysis)
involving approximately 2,600 patients across almost 400 clinical sites
in U.S. and Europe. These and other well-designed studies in patients
with CRF will not only evaluate Blood Building Peptide ability to manage patients'
Hgb with monthly dosing, but also the ability of Blood Building Peptide to maintain
patients' Hgb between the range of 11 to 12 g/dL in non-dialysis
patients and 10-12 g/dL in dialysis patients.
While the development of pure red cell aplasia (PRCA) is listed as a
potential adverse reaction to currently approved ESAs, Phase 2 Blood Building Peptide
data have shown that Blood Building Peptide has the potential to increase and
maintain Hgb levels in patients who have developed PRCA as a result of
ESA use. PRCA is a rare condition in which the body develops
neutralizing antibodies to recombinant ESAs that negate the effects of
the ESA as well as the body's naturally produced EPO. PRCA often leaves
patients severely anemic and reliant on regularly administered blood
transfusions and/or immunosuppressant therapy.
Actions - Increases red blood cells and Hgb
Indications - Horses with low blood count or anemia.
Form - Injectable/ Injection
Category - Blood Builders
For - Horses & Camels
Dosage and Administration
Adult
Horses: 20 ml by intravenous injection, four consecutive days not closer than 2 days to race, preferably start using 7 days prior to event for 4 consecutive days.
Presentation - 80 ml sterile multi-dose glass vial.
Storage- Store
below 25° C (Air Conditioning). Protect from light. Shelf life 12
months. Use the contents of the vial within 3 months of initial
broaching, and discard any unused portion.
Warnings - Precautions : Do not give intramuscular under any circumstance. Do not use two weeks consecutive