The Lactanase
Injection is an Enzymic modulator to reduce lactic acid accumulation and delay
muscle fatigue. Lactanase supplies nutrients important for the formation of
acetyl coenzyme A in the horse's body. Acetyl coenzyme A is the gateway to the
Krebs cycle, where the release of cellular energy takes place. This formula was
the first pre-performance supplement to focus on the need for acetyl coenzyme A
during intensive exercise, when the horse cannot rely upon oxygen for energy
release. Lactanase has been tested by Thoroughbred and Standardbred trainers
and veterinarians at the nation's leading racetracks. It is now available to
all horsemen for optimum support of horses involved in intensive exercise and
performance.
Contains:
Dichloro-acetic acid 120 ug/mL Sodium gluconate 250 mg/mL
Features and Benefits
-LACTANASE is used to help reduce the incidence of Tying Up by reducing the
buildup of lactic acid in muscle cells.
Indications:
LACTANASE contains dichloroacetic acid, which is an activator of the enzyme
pyruvate dehydrogenase. This enzyme plays a central role in the process of
lactic acid production during hard work.
Supplementation with dichloroacetic acid (DCA) results in activation of the
enzyme pyruvate dehydrogenase, leading to a reduction in the rate of lactic
acid production and accumulation in muscles. Elevated plasma lactate levels
result in a reduction in pH which contributes to muscle fatigue and decreased
muscle performance.
Supplementation with
DCA has been shown to reduce lactic acid accumulation during exercise, and
produce a significant delay in muscle fatigue.
The pathogenesis of Exertional Rhabdomyolysis (“Tying Up”) in horses is related
to lactic acidosis during exercise, and associated low muscle pH.
Sodium bicarbonate and dimethylglycine (DMG), which may help to reduce lactic
acid accumulation during exercise, have been used to assist in the prevention
of Tying Up in horses. Similarly, DCA (LACTANASE) results in a reduction in the
rate of lactate accumulation, and a delay in the onset of muscle fatigue.
Dosage and Administration
Give 20 - 40 mL by intravenous injection (diluted in 1 Litre saline, or
administer via catheter) 1 - 2 times weekly.
WARNING: Take care to
avoid leakage from the vein. LACTANASE is highly irritant if given outside the
vein. Avoid accidental contact with mucous membranes or eyes (avoid accidental
spillage or spray).
Presentation: 100 mL
sterile glass multi-dose vial.
Storage: Store below
25o C (air conditioning). Protect from light.
For: Race Horses, Dogs, Greyhounds, Camels
Trainers Tips:
Best used when given 20-40mL IV (diluted in 1 Litre saline, or administer via catheter)
24hrs prior to event. It is also good practice to give 20-40ml if Vitamin C day
before event.
